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Multi-vehicle injury crash stops traffic on Hwy. 101 near base of Cuesta Grade

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Update, 11:10 p.m.:

Five patients were transported from the multi-vehicle crash on Highway 101 on Saturday night, according to the San Luis Obispo County Fire Department.

In a post on X, the agency said the highway “was temporarily shut down in both directions to allow crews to safely operate.”

“Please drive with caution and remain alert, especially during nighttime travel,” the post said.

Traffic is stopped on southbound Highway 101 near the base of the Cuesta Grade after a multi-vehicle crash on Saturday night, March 28, 2026.
Traffic is stopped on southbound Highway 101 near the base of the Cuesta Grade after a multi-vehicle crash on Saturday night, March 28, 2026. Caltrans

Original story:

A multi-vehicle crash on the Cuesta Grade brought traffic to a standstill with potential multiple injuries on Highway 101 on Saturday night.

The crash was reported in the northbound lanes at 9:21 near Hawk Hill Lane, according to the Pulse Point app.

Multiple ambulances were requested at the scene, according to emergency radio traffic, and the CHP Traffic Information Page reported that one subject was in the roadway unresponsive.

The CHP page said a small black car was hit by an unknown type of vehicle. Then another vehicle hit one of the two involved in the original crash.

All three vehicles were reportedly being towed for evidence purposes.

This story was originally published March 28, 2026 at 10:03 PM.

CORRECTION: An earlier version of this story said the crash was in the southbound lanes of Highway 101. It was actually on the northbound side.

Corrected Mar 28, 2026
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Joe Tarica
The Tribune
Joe Tarica is the editor of The Tribune in San Luis Obispo. He’s worked in various newsroom roles since 1993, including as an award-winning copy editor, designer and columnist. A California native, he has been a resident of San Luis Obispo County for more than 35 years and is a Cal Poly graduate.
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