President Barack Obama predicted that professed Sept. 11 mastermind Khalid Sheikh Mohammed will be convicted and executed as Attorney General Eric Holder proclaimed: "Failure is not an option."

With Cyber Monday, the unofficial start of the Internet holiday shopping season nearing, a Senate committee Tuesday condemned three online companies, saying they are tricking consumers into signing up for subscription services they don't want.

An additional 6,700 doses of the H1N1 vaccine are on the way for San Luis Obispo public health officials to administer, and the vaccine should arrive in the area later this week.

The San Luis Obispo City Council voted unanimously tonight to remove a hotel owner from the board of the tourism business improvement district.

The search for Cuesta College’s new interim leader is on, school officials said Tuesday, and they hope to have someone before current President David Pelham steps down at the end of December.

Los Osos developer Jeff Edwards has filed suit to prevent the Board of Supervisors from taking action on the Los Osos wastewater project next Tuesday.

Atascadero police arrested two Paso Robles residents suspected of several North County retail and residential burglaries Monday.

An additional 6,700 doses of the H1N1 vaccine are on their way for San Luis Obispo public health officials to administer, and the vaccine should arrive in the area later this week.

A judge has denied Dan De Vaul's request for a new trial.

Malaria. Tuberculosis. Alzheimer's disease. AIDS. Pandemic flu. Genital herpes. Urinary tract infections. Grass allergies. Traveler's diarrhea. You name it, the pharmaceutical industry is working on a vaccine to prevent it.

California has unveiled a new consumer report card on five health insurers - and none got the top rating.

A building inspection led to the closure of the Gallery at the Old Schoolhouse in Cambria on Tuesday, the building’s owner has announced.

A look at the world's 10 most corrupt and 10 least corrupt countries according to the Corruption Perceptions Index report published Tuesday by watchdog Transparency International.

What word sums up 2009? How about unfriend?

Two Atascadero men were arrested Monday afternoon at Mitchell Park in San Luis Obispo and charged with possession of marijuana for sale.

Cuesta College President David Pelham has resigned from his role to lead another college in Abu Dhabi, a city in the United Arab Emirates along the Persian Gulf.

WASHINGTON - More than 15 million taxpayers may owe the government $250 or more because of how the IRS last spring set up President Barack Obama's tax break that was designed to help consumers spend the U.S. economy out of recession.

Most women don't need a mammogram in their 40s and should get one every two years starting at 50, a government task force said Monday. It's a major reversal that conflicts with the American Cancer Society's long-standing position.

The number of U.S. households that are struggling to feed their members jumped by 4 million to 17 million last year, as recession-driven job losses and increased poverty and unemployment fueled a surge in hunger, a government survey reported Monday.

A limited number of seasonal flu shots will be available at the 50+ Expo in Arroyo Grande on Tuesday.